Biotech Decontamination Technology
Advanced Decontamination Technology for Life Sciences & Biotechnology
Protecting Your Research. Securing Your Facility. Advancing Your Science.
What is SteraMist decontamination technology?
SteraMist is an EPA-registered ionized Hydrogen Peroxide (iHP) decontamination technology that achieves ≥6-Log pathogen reduction in under 60 minutes, with zero residue. It is used for biodecontamination of BSL labs, GMP cleanrooms, biosafety cabinets, and pharmaceutical manufacturing suites — replacing traditional vaporized hydrogen peroxide systems with faster, eco-friendly, and more material-compatible disinfection technology.
Core Capabilities
✔ Decontamination Technology— iHP validated to achieve ≥6-Log pathogen reduction
✔ Disinfection Technology— EPA-registered, broad-spectrum efficacy against bacteria, viruses, spores & fungi
✔ Biodecontamination— Full-room and surface-level treatment for high-containment environments
✔ Vaporized Hydrogen Peroxide Alternative— Faster cycles, superior material compatibility
Why Choose SteraMist iHP Decontamination Technology for Biotech?
| Why do biotech and pharma facilities choose SteraMist over vaporized hydrogen peroxide? SteraMist iHP outperforms traditional vaporized hydrogen peroxide in three key areas: cycle speed (4x faster than vaporized hydrogen peroxide), material compatibility (no corrosion of sensitive lab equipment), and ease of use (no extended aeration period required). It delivers the same ≥6-Log pathogen reduction as vaporized hydrogen peroxide while producing zero residue, breaking down to oxygen and humidity. |
The Science Behind iHP Disinfection Technology
SteraMist’s patented Binary Ionization Technology (BIT) converts a low-concentration hydrogen peroxide solution into ionized Hydrogen Peroxide (iHP) — a cold plasma of highly reactive hydroxyl radicals. These radicals rapidly oxidize microbial cell membranes and DNA, achieving validated biodecontamination without the hazards associated with traditional vaporized hydrogen peroxide systems.
- No residue: iHP breaks down to water vapor and oxygen — safe, clean, and residue-free.
- No corrosion: Unlike vaporized hydrogen peroxide, iHP is gentle on electronics, optics, and sensitive materials.
- No long aeration: Full decontamination technology cycles complete in under one hour, maximizing uptime.
- GMP/GxP validated: Documented IQ/OQ/PQ validation packages meet regulatory requirements. Get a quote for validation and qualification services today ➔
Where Is SteraMist Biodecontamination Technology Used?
What environments use SteraMist biodecontamination technology? SteraMist biodecontamination technology is used in BSL-2 and BSL-3 research laboratories, GMP pharmaceutical manufacturing suites, cleanrooms, fill/finish areas, biosafety cabinets, isolators, cell and gene therapy production facilities, and animal holding vivaria. It is validated for any controlled environment requiring documented, residue-free disinfection technology with ≥6-Log efficacy.
| BSL-2 / BSL-3 Labs Full-room biodecontamination validated for high-containment research environments. | GMP Manufacturing Suites Validated disinfection technology for pharma and biotech production areas. | Biosafety Cabinets & Isolators Complete decontamination technology for enclosed workspaces and containment units. |
| Cell & Gene Therapy Protect sensitive biologics from cross-contamination during production. | Animal Facilities Safe, residue-free treatment for vivaria and animal research spaces. | Cleanrooms & Fill/Finish Maintain stringent sterility requirements with validated decontamination technology. |
SteraMist iHP vs. Vaporized Hydrogen Peroxide & UV Systems
How is SteraMist different from vaporized hydrogen peroxide? While both SteraMist iHP and vaporized hydrogen peroxide achieve ≥6-Log pathogen reduction, iHP completes cycles in under 60 minutes versus 2–8+ hours for vaporized hydrogen peroxide, requires no extended aeration period, leaves zero residue, and is gentler on metals and sensitive equipment. SteraMist also provides true 3D volumetric coverage, penetrating spaces that line-of-sight UV systems cannot reach.
| Feature | SteraMist iHP | Vaporized Hydrogen Peroxide | UV/UVC Systems |
| Active Agent | Ionized H₂O₂ (iHP) | H₂O₂ Vapor | UV-C Light |
| Efficacy | ≥ 6-Log reduction | ≥ 6-Log reduction | 2–4 Log (surface only) |
| Coverage | 3D volumetric | Requires saturation | Line-of-sight only |
| Residue | None (H₂O + O₂) | Can leave residue | None |
| Material Safety | High — no corrosion | Moderate | High |
| GMP/GxP Validated | Yes | Yes | No |
* Based on independent third-party testing and published validation studies. Contact SteraMist for full validation data packages.
Regulatory Compliance for Biodecontamination Technology
Is SteraMist decontamination technology validated for GMP and FDA-regulated environments? Yes. SteraMist iHP is an EPA-registered disinfection technology and third-party validated against C. diff, Anthrax, SARS-CoV-2, and other high-priority pathogens. It supports FDA 21 CFR Part 11 and cGMP compliance documentation and has been validated per AOAC, EN 17272, and ISO 14937 standards. IQ/OQ/PQ validation support is available to meet regulatory facility qualification requirements.
- EPA-registered disinfectant effective against a broad-spectrum of pathogens.
- Supports FDA 21 CFR Part 11 and cGMP compliance documentation
- IQ/OQ/PQ validation support available for regulated facility qualification
- Compatible with USP <1072> and EU GMP Annex 1 contamination control strategies
Frequently Asked Questions About Biodecontamination Technology
Q: What is decontamination technology?
A: Decontamination technology refers to systems and methods used to eliminate or reduce microbial contamination, including bacteria, viruses, fungi, and spores, from surfaces, equipment, and enclosed spaces. In biotech and pharmaceutical settings, decontamination technology typically achieves a ≥6-Log (99.9999%) reduction in target pathogens and must be validated to meet GMP and regulatory standards.
Q: What is biodecontamination?
A: Biodecontamination is the process of removing or inactivating biological agents from a contaminated environment, surface, or piece of equipment using a validated chemical or physical method. In life sciences, biodecontamination is required for BSL labs, cleanrooms, GMP suites, and biosafety cabinets. SteraMist iHP is a validated biodecontamination technology that achieves ≥6-Log pathogen reduction with no residue.
Q: What is vaporized hydrogen peroxide and how does it work?
A: Vaporized hydrogen peroxide is a gaseous disinfection technology that uses H₂O₂ vapor at concentrations typically between 140–1,400 ppm to inactivate microorganisms. VHP achieves ≥6-Log reduction but requires extended cycle times of 2–8+ hours and a lengthy aeration period to clear residual gas before spaces are safe to re-enter. SteraMist iHP uses ionized hydrogen peroxide at much lower concentrations, completing biodecontamination quickly.
Q: Is SteraMist disinfection technology safe for sensitive lab equipment?
A: Yes. SteraMist iHP uses ionized hydrogen peroxide at very low concentrations (7.8% H₂O₂) and produces no corrosive residue. It is safe for use around electronics, optics, metals, stainless steel, plastics, and sensitive biotech instrumentation — unlike traditional vaporized hydrogen peroxide systems, which can corrode metals and damage materials at higher concentrations.
Q: What pathogens does SteraMist decontamination technology eliminate?
A: SteraMist iHP is EPA-registered and validated against a broad spectrum of pathogens, including SARS-CoV-2, Clostridioides difficile (C. diff) spores, Bacillus anthracis (Anthrax) spores, MRSA, norovirus, mycobacteria, and mold. It is effective against all four classes of microorganisms: bacteria, viruses, fungi, and bacterial endospores, making it a comprehensive biodecontamination technology for life sciences environments.
Q: Can SteraMist replace vaporized hydrogen peroxide in our facility?
A: In most cases, yes. SteraMist iHP is a validated alternative to vaporized hydrogen peroxide that delivers equivalent or superior ≥6-Log efficacy with shorter cycle times, zero residue, and better material compatibility. SteraMist offers full validation documentation (IQ/OQ/PQ) to support regulatory transitions from VHP-based programs. Contact SteraMist for a facility-specific assessment ➔
“We conducted a successful room disinfection study* in accordance with [pharmaceutical] cGMP specifications. [SteraMist] impressed with its robustness and standardized application.”
*Materials evaluated: Glass, Glass Reinforced Plastic (GRP), Arcoplast, Grade 316 Stainless Steel, High-Pressure Laminate (HPL), Mipolam BioControl EL5
Microbes evaluated: Escherichia coli, Staphylococcus aureus, Aspergillus brasiliensis, Candida albicans, Pseudomonas aeruginosa, Bacillus subtilis
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Get Started with SteraMist Decontamination Technology
Our team of biodecontamination specialists is ready to help you design the right decontamination technology strategy for your facility — whether you are evaluating an alternative to vaporized hydrogen peroxide, upgrading an existing disinfection technology program, or building a new contamination control protocol from the ground up.
