--- title: "SteraMist Integrated System (SIS)" date_published: "2023-10-09" date_modified: "2026-10-01" permalink: "https://www.steramist.com/offerings/products/steramist-integrated-system/" seo: title: "The SteraMist Integrated System - SteraMist" description: "SteraMist iHP technology integrated for enclosure decontamination. Fully integrate or use a mobile iHP system for enclosure decon." canonical_url: "https://www.steramist.com/offerings/products/steramist-integrated-system/" --- ![Port view of a SteraMist iHP nozzle integrated into a SIS enclosure](https://www.steramist.com/wp-content/uploads/2025/07/PortViewiHPSIS-v2-740x807.webp) Integrate SteraMist® **Into Enclosures** # SteraMist Integrated **System** (SIS) Integrate iHP into isolators, material transfers, sterilizers, hatches, biosafety cabinets, RABS, and more with the [SteraMist® Standalone](#standalone) system and [SteraMist Integrated System (SIS)](#sisintegrated). Whether you purchase a brand-new enclosure directly from our manufacturer, retrofit existing equipment, or aim to deliver disinfection beyond small-to-medium size enclosures, SteraMist® has your solution. • Compliant with GxP, Annex 1, 21 CFR Part 11, ISO 9001:2015/14001, and more. • Intuitive user interface, easy system calibration, and audio-visual cycle stage alarms. • Consistently achieve six-log and greater reductions without material damage. [Quote Your Integrated System](https://www.steramist.com/contact/) ## **Portable** Decontamination System ![SteraMist Standalone system with handheld applicator](https://www.steramist.com/wp-content/uploads/2025/07/Standalone-SIS-Handheld-1220x1366.webp) Portable System, **Flexible Integration** ## SteraMist® **Standalone** Designed for both integration and portability, the versatile **SteraMist Standalone** enables full area fogging and controlled enclosure decontamination into a single, compact system. Packed with features and controls, decontamination is finely tuned to deliver premium results. Able to connect to any mounted or freestanding applicator for fogging to deliver iHP decontamination in any industry. • Configure user profiles with individual access roles and customizable login credentials. • Save multiple enclosure profiles with automatic injection calculation based on area volume. • Able to move freely with integrated wheels and a retractable handle. • Simple user interface, easy calibration, and audio-visual cycle stage alarms. ![Icon representing compact, mobile deployment of the SteraMist Standalone](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Compact.png) ### Compact 8; Mobile for Quick Deployment Into Any Area ![Icon representing spraying and fogging with the SteraMist applicator](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Applicator.png) ### Freely Spray 8; Fog with Standard Applicator ![SteraMist Standalone system 90 degree applicator](https://www.steramist.com/wp-content/uploads/2025/07/Asset-8@2x.webp) ### Enhance Enclosures with Integrated Applicator [Get a Quote for the Standalone](https://www.steramist.com/contact/) ### Controlled Enclosure Decontamination Whether implementing iHP into a biosafety cabinet using an applicator and sash or a walled enclosure via a mounting flange, the SteraMist Standalone provides versatility in decontamination. ### Portable Room Fogging Move the SteraMist Standalone to any area in need of iHP decontamination, connect the standard applicator to a stand, and fully fog the space with comprehensive controls. ### Customized 8; Optimized Enclosure Decon Create a custom SteraBox enclosure to specification and create an optimized controlled environment with the SteraMist Standalone. SteraBox enclosure sold separately. ![SteraMist Standalone unit performing portable room fogging](https://www.steramist.com/wp-content/uploads/2025/07/Standalone-Fogging-Room-1440x801.webp) ![SteraMist Standalone connected to a biosafety cabinet for enclosure decontamination](https://www.steramist.com/wp-content/uploads/2025/07/Standalone-BSC-v2-1440x810.webp) ![SteraMist Standalone unit performing portable room fogging](https://www.steramist.com/wp-content/uploads/2025/07/Standalone-Fogging-Room-1440x801.webp) ![SteraBox acrylic custom enclosure for SteraMist decontamination](https://www.steramist.com/wp-content/uploads/2025/07/SteraBox-Acrylic-Photo-169-1440x810.webp) ## Introducing the SteraMist® SIS Standalone ![Video: Enclosure decontamination using SteraMist iHP technology](https://www.steramist.com/wp-content/uploads/2025/04/Enclosure-Decon_1280-x-720-740x416.jpg) [Watch Video](#video-block_5494d3fcbe48c0f0fb4c667eff377922) ![Retrofit integration of SteraMist iHP into an existing enclosure barrier](https://www.steramist.com/wp-content/uploads/2025/07/RetrofitBarrier-2-740x416.webp) Upgrade Existing Equipment with iHP® ## **Retrofit** Your Enclosures Avoid decommissioning operational equipment by integrating a SteraMist iHP into existing equipment. SteraMist engineers utilize existing enclosures, ports, wiring, and lines to seamlessly route iHP® into your enclosure. **For use with the SteraMist Standalone only.** • Connect the SteraMist Standalone to any retrofitted enclosure applicator and decontaminate using custom cycle profiles. • Upgrade your cleanroom environment with faster, superior SteraMist ionized Hydrogen Peroxide technology. • Interior and exterior mounting options are available to accommodate any small-to-medium sized spaces. [Contact Us To Retrofit](https://www.steramist.com/contact/) ## **Dedicated** Integrated Decontamination ![SteraMist Integrated System (SIS) 2-door pass-through enclosure, standing configuration](https://www.steramist.com/wp-content/uploads/2026/01/SIS-Passthrough-Standing-1220x1472.webp) Comprehensive Enclosure Integration ## SteraMist **Integrated System** (SIS) Fully integrate SteraMist components into pharmaceutical-grade stainless steel material transfers, sterilizers, hatches, and more with **SteraMist Integrated System (SIS)**. When seamlessly integrating iHP, we work directly with our select, trusted manufacturers to find the ideal controlled enclosure to suit any workflow. Select from a wide variety of prefabricated enclosures to introduce a specialized controlled environment exclusively designed for your space and materials, all powered by iHP decontamination. Purchase includes start-to-finish qualification 8; acceptance testing. • Reduce the risk of false-positive isolation results, cost of investigations, 8; eliminate production delays. • Available in a variety of structural, freestanding, 8; modular chambers. • Comprehensive user security options with data acquisition and management. • Fully customizable input and output configurations for full interoperability. ![SteraMist Integrated System (SIS) nozzle diagram](https://www.steramist.com/wp-content/uploads/2025/07/Asset-13@2x.webp) ### Dedicated, Integrated Low-Profile iHP Nozzle ![Icon representing full decontamination automation for SIS enclosures](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Automation.png) ### Full Decon Automation for Any Enclosure ![SteraMist system diagram manufacturing icon](https://www.steramist.com/wp-content/uploads/2025/07/Asset-8@2x-1-300x317.webp) ### iHP Integrated Directly from Manufacturer [Quote SteraMist® Integration](https://www.steramist.com/contact/) ![SteraMist Integrated System (SIS) 2-door pass-through enclosure, ceiling-mounted configuration](https://www.steramist.com/wp-content/uploads/2026/01/SIS-Passthrough-Ceiling-v3-740x416.webp) Value Beyond **Results** ## Maintain Enclosure Integrity with iHP Maintaining controlled enclosures using ionized Hydrogen Peroxide delivers more than just speed and reductions. With non-corrosive BIT Solution and cold plasma science, SteraMist technology features incredible surface compatibility proven by years of field and laboratory performance. Save on replacement costs and avoid damaging valuable equipment while protecting the lifespan of your sterile space. ## **SteraBox:** Create Your Own Custom Enclosure Compatible with both the SteraMist Standalone and Environment System, the SteraBox is a fully-customizable small-to-medium size enclosure for use exclusively with SteraMist. Built to client specification and primarily designed for non-sterile environments, the SteraBox injects iHP mist into a chamber and cleanly vents into the surrounding area using HEPA filtration with carbon filter stack. For full integration into sterile environments, see the [SteraMist Integrated System (SIS)](#sisintegrated). ![SteraMist Integrated System (SIS) integrated into a pharmaceutical-grade stainless steel enclosure](https://www.steramist.com/wp-content/uploads/2024/11/SIS-Enclosure-1220x660.webp) ![Icon representing 360-degree iHP coverage inside the SteraBox](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_360-Reach.png) ### ionized Hydrogen Peroxide (iHP) Fills Enclosure for 360° Coverage ![Icon representing expanded fogging area](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Greater-Cubic-Feet.png) ### Accommodate Any Space 8; Decontamination with Custom Sizes ![SteraMist Standalone system 90 degree applicator](https://www.steramist.com/wp-content/uploads/2025/07/Asset-8@2x.webp) ### Exclusively Designed to Integrate SteraMist Systems ![Icon representing cGMP, GMP, and ISO compliance](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Checkmark.png) ### Constructed to Comply with Critical cGMP, GMP, ISO Standards ![Icon representing enclosure and equipment protection with iHP](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Maintenance.png) ### Choose the Material, Layout, 8; Function of Your Custom Enclosure ![Icon representing faster decontamination cycles](https://www.steramist.com/wp-content/uploads/2024/11/Icon-Borderless_Speed.png) ### Receive a Faster Decon Tailored to Your Enclosure 8; Equipment ### Configuration **Options** - **Available Variations:** Cabinet, 2-Door Pass Through - **Dimensions/****Weight:** *Varies per Specification* - **Shelving:** Tiered Wire Shelving (*Optional*) - **Applicator Compatibility:** Standard Applicator, Integrated Applicator - **Filtrations:** Mounted Blower w/ Active Carbon Filter - **Wall Configurations:** Single, Double ![SteraMist Integrated Platform resource cover](https://www.steramist.com/wp-content/uploads/2026/06/Integrated_Platform_Cover-980x551.webp) Find Your **Ideal Integration** ## **SteraMist® Integration System** Platform Interested in making SteraMist® iHP® an integral part of your aseptic enclosure decontamination? Our comprehensive booklet is the perfect guide to discovering how SteraMist® can assist in streamlining your workflow and improving outcomes. [iHP® Integration Brochure](https://www.steramist.com/integration-catalog/) ## **Frequently Asked Questions** for the SteraMist Integrated System (SIS) Platform ### **What is the SteraMist Integrated System Platform?** The SteraMist Integrated System is a family of configurations that integrate SteraMist's ionized Hydrogen Peroxide (iHP) technology into enclosures such as isolators, material transfers, sterilizers, hatches, biosafety cabinets, and RABS. It includes the portable SteraMist Standalone, retrofit options for existing equipment, the fully integrated SteraMist Integrated System (SIS) for pharmaceutical-grade stainless steel enclosures, and the custom SteraBox enclosure. Across these configurations, the technology consistently achieves six-log and greater reductions without material damage. ### **What is the difference between the SteraMist Standalone, Retrofit, and the SIS options?** The SteraMist Standalone is a compact, portable unit with integrated wheels and a retractable handle that performs both full-room fogging and controlled enclosure decontamination. Retrofit connects a Standalone unit to an existing enclosure's ports, wiring, and lines to add iHP decontamination without decommissioning the equipment. The SteraMist Integrated System (SIS) goes further, fully integrating iHP components, including a dedicated, low-profile iHP nozzle, directly into pharmaceutical-grade stainless steel material transfers, sterilizers, and hatches built with SteraMist's select trusted manufacturers. ### **What is included when I purchase a SteraMist Integrated System (SIS)?** Every SIS purchase includes start-to-finish qualification and acceptance testing. SIS enclosures also come with fully customizable input and output configurations for interoperability, comprehensive user security options, and data acquisition and management capabilities, helping reduce the risk of false-positive isolation results, investigation costs, and production delays. ### **What is the SteraBox, and how does it relate to the rest of the Integrated System lineup?** The SteraBox is a fully customizable small-to-medium enclosure designed exclusively for use with the SteraMist Standalone and Environment System, primarily for non-sterile environments. It injects iHP mist into the chamber for 360-degree coverage and vents cleanly through HEPA filtration with a carbon filter stack; it's available in Cabinet or 2-Door Pass-Through variations with optional tiered wire shelving and single- or double-wall configurations. For full integration into sterile environments, SteraMist recommends the SteraMist Integrated System (SIS) instead. ### **What compliance standards does the SteraMist Integrated System Platform meet?** The Integrated System lineup is compliant with GxP, Annex 1, 21 CFR Part 11, and ISO 9001:2015/14001 standards. Specifically constructed to comply with cGMP, GMP, and ISO standards, supporting use in regulated pharmaceutical and controlled environments. ### **How does iHP protect enclosure materials during decontamination?** SteraMist's ionized Hydrogen Peroxide uses a non-corrosive BIT Solution and cold plasma science, giving it strong surface compatibility that's been proven through years of field and laboratory performance. This helps facilities avoid damaging valuable equipment, reduce replacement costs, and protect the lifespan of the sterile space, while still consistently achieving six-log and greater reductions. ![SteraMist iHP disinfection and decontamination products and services catalog](https://www.steramist.com/wp-content/uploads/2025/06/Site-Catalog-Image_1600-x-1080-980x551.jpg) Discover SteraMist iHP ## **Products 8; Services** Catalog View a comprehensive catalog of SteraMist iHP Disinfection and Decontamination Products 8; Services. [Products 8; Services Catalog](https://www.steramist.com/products-services-catalog/) ## Request a Quote for SteraMist Integrated Systems Tell us about your enclosure, isolator, or facility. Our team will help you find the right SteraMist iHP integration, from a portable Standalone system to a fully custom SIS build. ![SteraMist iHP Integration Suite for enclosures, isolators, RABS](https://www.steramist.com/wp-content/uploads/2026/05/IntegrationSuite-1024x926.webp)